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Have a very digenetic life cycle, involving a motile, extracellular promastigote stage that parasitizes the alimentary tract of the sandfly vector and an immotile amastigote phase that survives and replicates within the phagolysosomes of mononuclear phagocytes [2,3]. In addition to human beings, Main hosts of LeishmaniaLister 427 cells. Trypanosome